Non-Cancerous Causes That Can Elevate PSA Levels

Non-Cancerous Causes That Can Elevate PSA Levels

Prostate specific antigen (PSA) is a protein that is produced by the prostate gland. Elevated levels of the protein in the bloodstream can often be an early indicator of prostate problems, such as prostate cancer. However there are also many non-cancerous causes for PSA levels to be elevated. Conditions such as infection, inflammation, and injury can all trigger a potential rise in PSA. Here are some possible reasons why your PSA level may be above normal.

Benign Prostatic Hyperplasia (BPH)

BPH is essentially a wealth of additional cells. An overabundance of cells leads to an elevation in PSA production. This condition may require no treatment unless it begins to cause urination difficulties or urgency.


Inflammation of the prostate, or prostatitis, can increase the level of PSA in the blood. Prostatitis is believed to be related to any of several forms of bacterial infection and can be acute or chronic in nature. Treatment for prostatitis involves symptom relief through muscle relaxants, pain relievers, and massage. Bacterial prostatitis in particular is generally treated with antibiotics.


While elevations are usually only slight, intercourse can temporarily raise prostate levels. Because of this, most physicians will advise you to avoid any sexual activity for at least a couple of days before your PSA blood test.


Even without any prostate problems, as you age, PSA levels will naturally rise and may be entirely benign.

Prostate Trauma

Simple trauma to the prostate can easily elevate PSA levels causing false positives and undue worry. You should allow your body adequate time to recover prior to testing.

Urinary tract infection (UTI)

Any kind of infection of the prostate gland, including a UTI, can irritate and inflame prostate cells and cause PSA levels to rise. If you’ve been diagnosed with a urinary tract infection, be sure to wait until after the infection has cleared up before getting a PSA test.


Physical activity has been implicated as being a potential factor in elevating PSA levels, with bicycling in particular receiving the most scrutiny. While some studies have shown how strenuous bicycling can mildly elevate PSA levels other research findings however have been inconsistent.

Don’t allow an elevated PSA level to create any unwarranted anxiety. Stay up to date on all of your appointments, tests and rechecks. In addition to listening to your doctor and taking good care of your body. Even if your PSA elevation turns out to be cancerous, you can live a long, healthy life with the proper care and treatment.


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Dr. David Samadi M.D.

Dr. David Samadi is a board certified urologic oncologist trained in open and traditional and laparoscopic surgery and is an expert in robotic prostate surgery. He is Chairman of Urology, and Chief of Robotic Surgery at Lenox Hill Hospital.

Dr. David Samadi is also part of the Fox News Medical A Team as a medical correspondent and the Chief Medical Correspondent for am970 in New York City. He has dedicated his distinguished career to the early detection, diagnosis and treatment of prostate cancer and is considered one of the most prominent surgeons in his field.


For more comprehensive information about prostate cancer, detecting prostate cancer, how to live with prostate cancer, and how to help support the fight against prostate cancer, please visit:
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For more up to date prostate cancer news, please visit: Prostate Cancer 911


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